Dr. Dominic D'Agostino

This podcast is with Dr. Dominic D'Agostino, an assistant professor at the University of South Florida in Tampa and all-around expert on ketosis.

In this podcast we discuss:

• (00:00) Introduction
• (03:46) Ketosis has abundant therapeutic potential 
• (10:20) What to eat to maintain nutritional ketosis
• (19:58) Does a high-fat diet harm the gut?
• (29:14) Adaptations to a ketogenic diet expand mitochondrial capacity
• (38:45) How the brain uses ketones
• (46:36) Ketones improve Alzheimer's symptoms (unless you have an APOE4 allele)
• (57:17) Are ketone supplements a "magic pill?"
• (01:07:32) Why cancer cells may need sugar
• (01:23:51) Metformin is more than a diabetes drug
• (01:30:33) The body creates sugars while in ketosis
• (01:36:21) Restricting glutamine to slow cancer growth
• (01:43:24) Ketone supplements taste awful, but likely improve health

If you’re interested in learning more, you can read the full show notes here.

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Dr. Peter Attia

Peter is the founder of Attia Medical, a medical practice with offices in San Diego and New York City, focusing on the applied science of longevity and optimal performance.

In addition to being a medical doctor, Dr. Attia has done research on the role of regulatory T cells in cancer regression and other immune-based therapies for cancer. Regulatory T cells have also been, in the past, referred to as suppressor T cells because of their role in actually attenuating or reducing the inflammatory response.

Dr. Attia and I share interests in all things related to longevity and healthspan, which includes the role of diet, nutrition, sleep, exercise, and stress. Dr. Attia is a medical doctor and specializes in implementing these strategies in clinical practice. You can learn more about that at his website www.attiamedical.com.

In this episode, we discuss...

• (00:00) Introduction
• (05:39) The difficulty of identifying longevity compounds
• (08:41) The mTOR and IGF-1 growth/longevity pathways 
• (19:11) Preventing cell and tissue damage to live longer
• (22:28) Dr. Attia's ideal diet for prolonging lifespan
• (25:45) Measuring gut microbes is challenging 
• (35:34) Alzheimer's disease risk is more lifestyle than genetics
• (42:05) Environmental triggers of Alzheimer’s disease
• (55:49) What prolonged fasting teaches us about metabolism
• (53:36) Healing brain injury and concussion with metabolism

If you’re interested in learning more, you can read the full show notes here.

Join over 300,000 people and get the latest distilled information straight to your inbox weekly: https://www.foundmyfitness.com/newsletter

Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A’s with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor