Dr. Ronald Krauss

Dr. Ronald Krauss, M.D. is the director of atherosclerosis research at Children’s Hospital Oakland Research Institute, Adjunct Professor at UCSF and UC Berkeley. Dr. Krauss is really one of the pioneering scientists that changed the way we all think about cholesterol and saturated fat. He developed an assay that allows the quantification of low density lipoprotein particle size and concentration (known to the wider world as LDL cholesterol) based on a technique which determines the size of the particle based on physics...meaning the speed at which it flies through the air.

In this episode, we discuss...

• (00:00) Introduction
• (03:58) An overview of lipoproteins – HDL, LDL, and VLDL 
• (09:32) Cholesterol is a “passenger” on a train  
• (12:09) LDL vs HDL - why one is dangerous and the other isn’t
• (17:42) Raising HDL doesn’t reduce heart disease risk the same way as lowering LDL 
• (19:13) Leaky gut and inflammation increase VLDL production to protect the body
• (30:38) The misconception that dietary cholesterol significantly raises blood cholesterol
• (40:56) Saturated fats vs carbohydrates in raising cholesterol and CVD risk
• (53:08) Statins are a reliable, but imperfect, therapy for lowering CVD risk
• (01:08:20) Measuring cholesterol particle size refines risk assessment and informs medication use

If you’re interested in learning more, you can read the full show notes here.

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CHORI Bar Team

Meet some of the CHORI bar team: Dr. Bruce Ames, Dr. Joyce McCann, and Dr. Mark Shigenaga.

On this podcast we talk about the different types of HDL and LDL cholesterol and what they do in the body. We discuss a low-calorie, micronutrient- and fiber-dense nutrition bar (referred to as the CHORI bar) that Bruce and I briefly touched on in a previous conversation, how each of the components of the bar from the vitamins and minerals to the fiber and polyphenols are all really important but have separate functions in the body that can work together in much the same way an orchestra play their individual parts to create a symphony that is larger than their individual roles, how the chori bar raised a certain type of HDL in lead adults in just two weeks, how eating the CHORI bar raised HDL, lowered triglycerides and small LDL particles, and improved insulin sensitivity after eight weeks in overweight/obese individuals all without them changing their diet.

The CHORI bar is not available for consumers yet but you can keep up with choribar updates on bruceames.org/choribar.

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Dr. Aubrey de Grey

Dr. Aubrey de Grey is a biomedical gerontologist and the founder of the SENS research foundation which aims to find technologies that can repair the various types of damage that occur during the aging process.

In this episode, we discuss...

• 00:00:00 - Introduction
• 00:02:27 - How to understand aging
• 00:08:14 - Epigenetic modifications accommodate cellular aging
• 00:18:24 - Inflammation is a double-edged sword 
• 00:24:00 - Parabiosis has the potential to slow aging 
• 00:31:35 - Lifestyle factors can only extend lifespan so far
• 00:36:49 - Future of Crispr/Cas9 in aging research
• 00:40:56 - Utilizing pluripotent stem cells from the placenta

You can find Aubrey on Twitter at @aubreydegrey, and his foundation at www.sens.org.

If you’re interested in learning more, you can read the full show notes here: https://www.foundmyfitness.com/episodes/aubrey-de-grey

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Dr. Rhonda Patrick answers some of the most popular questions regarding vitamin D including:

• (00:00) Introduction
• (02:22) How do you decide how much vitamin D to supplement with?
• (12:51) Is it possible to get too much vitamin D?
• (20:52) Is there a difference between vitamin D made from the sun versus a supplement?
• (24:43) What form of vitamin D is more bioavailable or absorbed better?

Join over 300,000 people and get the latest distilled information straight to your inbox weekly: https://www.foundmyfitness.com/newsletter

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