Dr. Dominic D'Agostino

This podcast is with Dr. Dominic D'Agostino, an assistant professor at the University of South Florida in Tampa and all-around expert on ketosis.

In this podcast we discuss:

• 00:00:00 - Introduction
• 00:03:46 - Ketosis has abundant therapeutic potential 
• 00:10:20 - What to eat to maintain nutritional ketosis
• 00:19:58 - Does a high-fat diet harm the gut?
• 00:29:14 - Adaptations to a ketogenic diet expand mitochondrial capacity
• 00:38:45 - How the brain uses ketones
• 00:46:36 - Ketones improve Alzheimer's symptoms (unless you have an APOE4 allele)
• 00:57:17 - Are ketone supplements a "magic pill?"
• 01:07:32 - Why cancer cells may need sugar
• 01:23:51 - Metformin is more than a diabetes drug
• 01:30:33 - The body creates sugars while in ketosis
• 01:36:21 - Restricting glutamine to slow cancer growth
• 01:43:24 - Ketone supplements taste awful, but likely improve health

If you’re interested in learning more, you can read the full show notes here: https://www.foundmyfitness.com/episodes/dominic-dagostino

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Dr. Peter Attia

Peter is the founder of Attia Medical, a medical practice with offices in San Diego and New York City, focusing on the applied science of longevity and optimal performance.

In addition to being a medical doctor, Dr. Attia has done research on the role of regulatory T cells in cancer regression and other immune-based therapies for cancer. Regulatory T cells have also been, in the past, referred to as suppressor T cells because of their role in actually attenuating or reducing the inflammatory response.

Dr. Attia and I share interests in all things related to longevity and healthspan, which includes the role of diet, nutrition, sleep, exercise, and stress. Dr. Attia is a medical doctor and specializes in implementing these strategies in clinical practice. You can learn more about that at his website www.attiamedical.com.

In this episode, we discuss...

• 00:00:00 - Introduction
• 00:05:39 - The difficulty of identifying longevity compounds
• 00:08:41 - The mTOR and IGF-1 growth/longevity pathways 
• 00:19:11 - Preventing cell and tissue damage to live longer
• 00:22:28 - Dr. Attia's ideal diet for prolonging lifespan
• 00:25:45 - Measuring gut microbes is challenging 
• 00:35:34 - Alzheimer's disease risk is more lifestyle than genetics
• 00:42:05 - Environmental triggers of Alzheimer’s disease
• 00:55:49 - What prolonged fasting teaches us about metabolism
• 00:53:36 - Healing brain injury and concussion with metabolism

If you’re interested in learning more, you can read the full show notes here: https://www.foundmyfitness.com/episodes/peter-attia

Join over 300,000 people and get the latest distilled information straight to your inbox weekly: https://www.foundmyfitness.com/newsletter

Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A’s with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor