FoundMyFitness

In this interview, Dr. Rhonda Patrick talks to Dr. Frans Kuypers about his lab’s discovery on how the human placenta is a rich source of pluripotent stem cells, and yet the placenta is thrown away after delivery.

In this episode, we discuss... 

  • (00:00) Introduction 
  • (04:39) The human placenta as a source of hematopoietic cells
  • (11:30) Pluripotent cells can differentiate into any cell in the human body
  • (13:03) Public banking of abundant pluripotent placental stem cells
  • (18:06) Therapeutic applications of stem cells
  • (22:56) Stem cells as part of a physician’s toolkit 
  • (28:56) Epigenetics of induced pluripotent stem cells
  • (34:49) Biogenerators could use young cells to produce growth factors and other chemicals 
  • (38:36) Transferring blood from young mice into old mice regenerates tissues using GDF11
  • (43:32) Opportunities and challenges of banking stem cells
  • (52:49) Stem cells could eliminate deaths due to lack of bone marrow donors
  • (56:37) The way we fund research isn’t optimal for society

If you’re interested in learning more, you can read the full show notes here.

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Direct download: frans_kuypers_1.mp3
Category:general -- posted at: 8:01pm EST

Dr. George A Brooks

Dr. George A Brooks, an expert in exercise physiology and lactate metabolism. Lactate, a once demonized molecule thought to form lactic acid and become a dead-end toxic metabolite, has been vindicated by the work of Dr. Brooks, his colleagues, and others. 

In this episode, we discuss... 

  • (00:00) Introduction
  • (01:40) Dr. Brooks’ experience as an athlete inspired his research on lactate
  • (06:50) Lactate and its relationship to muscle fatigue is misunderstood
  • (09:10) Adaptations to exercise improve mitochondrial functioning and lactate metabolism
  • (14:14) How to use lactate threshold training to improve performance
  • (23:49) Lactate improves brain health and cognitive function 
  • (26:45) Lactate improves outcomes of traumatic brain injury via metabolism
  • (30:00) Lactate spares glucose, increasing antioxidants such as glutathione
  • (42:50) Early lactate administration following a traumatic brain injury is necessary, but challenging
  • (48:20) Lactate from exercise improves Parkinson's disease 
  • (55:00) Brain metabolism following traumatic brain injury

If you’re interested in learning more, you can read the full show notes here.

Join over 300,000 people and get the latest distilled information straight to your inbox weekly: https://www.foundmyfitness.com/newsletter

Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A’s with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor

Direct download: george_brooks_1.mp3
Category:general -- posted at: 6:45pm EST

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