#029 Jed Fahey, Sc.D. on Isothiocyanates, the Nrf2 Pathway, Moringa & Sulforaphane Supplementation

Dr. Jed Fahey is a multi-decade veteran of isothiocyanate research and is the director of the Cullman Chemoprotection Center at Johns Hopkins University.

In this episode, you'll discover:

• (00:00) Introduction
• (03:44) What is sulforaphane?
• (10:25) The NRF2 pathway, a master regulator of antioxidants
• (14:22) Cruciferous vegetables are rich sources of sulforaphane
• (20:39) Does cooking broccoli destroy sulforaphane? 
• (26:00) Sulforaphane supplements vary widely in quality
• (36:41) Antibiotics wipe out sulforaphane-producing bacteria in the gut
• (46:44) Managing Helicobacter pylori growth with a sulforaphane-rich diet
• (56:15) Sulforaphane reduces inflammation, but does it extend lifespan?
• (01:11:31) The therapeutic potential of sulforaphane for autism spectrum disorders, Alzheimer's disease, and schizophrenia
• (01:22:44) Research challenges and clinical trials
• (01:30:51) Is sulforaphane an anti-depressant?
• 01:34:50 - Moringin from moringa may be an alternative to sulforaphane with similar bioaction
• (01:53:55) How to maximize sulforaphane conversion
• (02:13:27) Testing the anticancer power of sulforaphane 

If you’re interested in learning more, you can read the full show notes here.

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